Parallel purine-pyrimidine-purine triplex: experimental evidence for existence
نویسندگان
چکیده
منابع مشابه
Protonated pyrimidine-purine-purine triplex
We have studied a protonated pyrimidine-purine-purine (Py-Pu-Pu) triplex, which is formed between the d(C)nd(G)n duplex and the d(AG)m oligonucleotide as the third strand and carries the CG*A+ protonated base-triads. We have observed such an intermolecular complex between a plasmid carrying the d(C)18 d(G)18 insert and the d(AG)5 oligonucleotide without bivalent cations in 200 mM of Na+ at pH4....
متن کاملParallel-stranded duplex DNA containing blocks of trans purine-purine and purine-pyrimidine base pairs.
A 30 base pair parallel-stranded (ps) duplex ps-L1.L2 composed of two adjoined purine-purine and purine-pyrimidine sequence blocks has been characterized thermodynamically and spectroscopically. The 5'-terminal 15 residues in both strands ('left-half') consisted of the alternating d(GA)7G sequence that forms a ps homoduplex secondary structure stabilized by d(G.G) and d(A.A) base pairs. The 3'-...
متن کاملPurine and pyrimidine metabolism.
The pathways of purine biosynthesis and degradation have been elucidated during the last 30 years; the regulation of the mechanisms involved is not yet fully understood, particularly with respect to quantitative aspects. Research into inborn errors of purine metabolism has provided valuable insights into purine synthesis and salvage pathways. Nutrition experiments using purine-free formula diet...
متن کاملReview Purine and pyrimidine receptors
Adenosine 5’-triphosphate (ATP), in addition to its intracellular roles, acts as an extracellular signallingmolecule via a rich array of receptors, which have been cloned and characterised. P1 receptors are selective for adenosine, a breakdown product of ATP, produced after degradation by ectonucleotidases. Four subtypes have been identified, A1, A2A, A2B and A3 receptors. P2 receptors are acti...
متن کاملPurine and pyrimidine metabolism by estuarine bacteria
Nucleotide bases are ubiquitous in living organisms, but the fate of these compounds in natural environments is poorly understood. Here we studied the metabolism of selected purines and pyrimidines in estuarine bacterial assemblages from the Øresund, Denmark. Depletion of nucleotide bases in the incubations was followed by the appearance of urea. The purine guanine and the catabolic intermediat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: FEBS Letters
سال: 1995
ISSN: 0014-5793
DOI: 10.1016/0014-5793(95)00519-f